Your Best Shot: The Personalized System for Optimal Weight Health―GLP-1 Shot or Not Hardcover – January 6, 2026

USA Today BestsellerThe real revolution of the GLP-1 shots is the insight that the body regulates appetite and more with the hormones GLP-1, GIP, PYY, and CCK—and with Your Best Shot in hand, you can learn to optimize their function and your weight health for life.Whether you have a little or a lot of fat to lose, cravings to curb, or use a shot or don’t, weight health hormone optimization is your best shot. Over two decades of research in her practice, renowned weight health expert Ashley Koff, RD, developed this game-changing system for patients and practitioners. Taking your best shot, you:determine whether your weight-health hormone function is suboptimalidentify your suboptimal-function type and narrow down causesget specific, targeted, doable recommendationsuse experiments to lock in on your better choicesdevelop strategies to tune out food noise and fight infobesitylearn how to vet the growing number of weight-health hormone-targeting medications, supplements, and devicesdiscover why better, not perfect, is the route to optimized healthchoose the methods and tools you'll use to reset your course whenever life happensThis evidence-based program is for anyone pursuing weight health—the majority of us not using a weight health hormone replacement, along with the millions who are, or are ready to come off it.Your Best Shot is not another plan. It’s your plan. Read more